03 Feb 2021 – Destiny Pharma announces Brazilian Patent granted for XF-73 nasal gel

Destiny Pharma plc
(“Destiny Pharma” or “the Company”)

Destiny Pharma Announces
Brazilian Patent Granted for XF-73 nasal gel preventing post-surgical infections

Brighton, United Kingdom – 3rd February 2021 – Destiny Pharma plc (AIM: DEST), a clinical stage innovative biotechnology company focused on the development of novel medicines that can prevent life threatening infections, today announces that Brazil’s Industrial Property Office has issued a notice of allowance that will now lead to the final approval in March of the Company’s patent application (Brazilian Patent Application no. PI 0512563-4) in relation to XF-73.

Neil Clark, Chief Executive Officer of Destiny Pharma, said: “We are very pleased to obtain this additional patent award (PI 0512563-4) from Brazil’s Industrial Property Office. We now have 84 issued patents from three patent families related to our XF platform that will provide strong protection to our XF-73 nasal gel product, alongside standard market exclusivity awards, in all major territories.

We recently completed enrollment in our Phase 2b clinical trial testing XF-73 nasal gel as a novel product preventing the incidence of post-surgical infections such as MRSA. We are now looking forward to announcing the full results of this study towards the end of March 2021 and planning the Phase 3 clinical programme. There is also a significant commercial opportunity for XF-73 in the hospital setting which we estimate could generate peak annual product sales of $1 billion in the US alone.”

XF-73 is a first-in-class drug candidate from Destiny Pharma’s XF platform, initially being developed for the prevention of postsurgical staphylococcal infections, such as methicillin-resistant Staphylococcus aureus (MRSA), which cause significant complications and
increased healthcare costs in the hospital setting. It has been awarded both qualifying infectious disease product (QIDP) and Fast Track status by the US FDA.

For further information, please contact:

Destiny Pharma plc
Neil Clark, CEO
Shaun Claydon, CFO
pressoffice@destinypharma.com
+44 (0)1273 704 440

Optimum Strategic Communications
Mary Clark, Shabnam Bashir, Manel Mateus
DestinyPharma@optimumcomms.com
+44 (0) 203 174 1789

finnCap Ltd (Nominated Advisor Joint Broker)
Geoff Nash / Kate Bannatyne, Corporate Finance
Alice Lane, Corporate Broking
+44 (0) 207 220 0500

WG Partners (Joint Broker)
Nigel Barnes / Claes Spång / Nigel Birks
+44 (0) 203 705 9330

About Destiny Pharma

Destiny Pharma is a clinical stage, innovative biotechnology company focused on the development of novel medicines that can prevent life-threatening infections. Its pipeline has novel microbiome-based biotherapeutics and XF drug clinical assets including NTCD-M3, a Phase 3 ready treatment for the prevention of C. difficile infection (CDI) recurrence which is the leading cause of hospital acquired infection in the US and also XF-73 nasal gel, which is in a Phase 2b clinical trial targeting the prevention of postsurgical Staphylococcal hospital infections including MRSA. It is also co-developing SPOR-COV, a novel, biotherapeutic product for the prevention of COVID-19 and other viral respiratory infections and has earlier grant funded XF research projects.

For further information, please visit https://www.destinypharma.com

02 Feb 2021 – Destiny Pharma to join panel discussion at the 7th Annual LSX World Congress 2021

Destiny Pharma PLC
(“Destiny” or “the Company”)

Destiny Pharma to Participate in Panel Discussion at the 7th Annual LSX World Congress 2021

Brighton, UK, 2 February 2021 – Destiny Pharma plc (AIM: DEST), a clinical stage innovative biotechnology company focused on the development of novel medicines that can prevent life threatening infections, announces that Neil Clark, Chief Executive Officer, will be taking part in a panel discussion at the 7th Annual LSX World Congress to be held virtually between 1-5 February, 2021.

The panel discussion ‘Investing In Infectious Disease – How Will The Covid Pandemic Transform The Development, Commercialisation, And Partnering Landscape?’ will be held at 15:00 GMT on 2nd February 2021.

The panel will be made available through the conference website and will be available to registered participants throughout the event – www.lsxleaders.com/lsx-world-congress.

– Ends –

Enquiries:

Destiny Pharma plc
Neil Clark (Chief Executive Officer)
Shaun Claydon (Chief Financial Officer and Company Secretary)
+44 (0) 1273 704 440

finnCap Limited – Nominated Adviser and Joint Broker
Geoff Nash / Kate Bannatyne / Charlie Beeson (Corporate Finance)
Alice Lane (ECM)
+44 (0) 20 7220 0500

WG Partners LLP – Joint Broker
Nigel Barnes / Claes Spång / Nigel Birks / Andrew Craig
+44 (0) 20 3705 9330

Optimum Strategic Communication
Mary Clark / Shabnam Bashir / Manel Mateus
+44 (0) 203 174 1789

About Destiny Pharma
Destiny Pharma is a clinical stage, innovative biotechnology company focused on the development of novel medicines that can prevent life-threatening infections. Its pipeline has novel microbiome-based biotherapeutics and XF drug clinical assets including NTCD-M3, a Phase 3 ready treatment for the prevention of C. difficile infection (CDI) recurrence which is the leading cause of hospital acquired infection in the US and also XF-73 nasal gel, which is in a Phase 2b clinical trial targeting the prevention of post-surgical Staphylococcal hospital infections including MRSA. It is also co-developing SPOR-COV, a novel, biotherapeutic product for the prevention of COVID-19 and other viral respiratory infections and has earlier grant funded XF research projects.

02 Feb 2021 – Destiny Pharma appoints Professor Mark Wilcox to Scientific Advisory Board

Destiny Pharma plc
(“Destiny Pharma” or “the Company”)

Destiny Pharma plc strengthens its Scientific Advisory Board with the appointment of Professor Mark Wilcox

A recognised leader in UK/NHS infection prevention and control, and a renowned expert in C. difficile infection

Brighton, United Kingdom – 2 February 2021 – Destiny Pharma Plc (AIM: DEST) a clinical stage innovative biotechnology company focused on the development of novel medicines that can prevent life threatening infections, today announces the appointment of Professor Mark Wilcox to its Scientific Advisory Board (SAB).

Professor Wilcox is a consultant microbiologist and Head of R&D in Microbiology at the Leeds Teaching Hospitals and is Lead on Clostridium difficile infection for Public Health England (PHE). He also has advisory roles to UK SAGE (COVID-19), NHS England’s Infection Prevention & Control national team and PHE’s Rapid Review Panel (reviewing the utility of infection prevention and control products for the NHS), and is a member of the UK NHS Antimicrobial Resistance Programme Board.

Dr Bill Love, Chief Scientific Officer of Destiny Pharma, commented, “We are pleased to welcome Professor Wilcox who is a recognised leader in UK/NHS infection prevention and control and a globally renowned expert in C. difficile infection. His knowledge compliments the existing expertise on our SAB as we plan for Phase 3 trials for our recently acquired asset, NTCD-M3, which is targeting the prevention of C. difficile infection recurrence. Professor Wilcox also brings an expert understanding of MRSA and COVID-19 hospital infections which is valuable insight for Destiny Pharma’s other preventative products in development, namely XF-73 and SPOR-COV.”

Professor Mark Wilcox, added, “NTCD-M3 is a novel way to out-compete pathogenic C. difficile that can remain in the gut after antibiotic treatment of C. difficile infection. I am greatly encouraged by the animal model and clinical trial data that support the ambition to use M3 to reduce the risk of recurrent C. difficile infection, which is the Achilles’ heel of antibiotic therapy.”

Professor Wilcox leads a Healthcare Associated Infection Research Group at the University of Leeds (http://medhealth.leeds.ac.uk/hcai), comprising ~30 doctors, scientists and nurses. Projects include multiple aspects of Clostridium difficile infection, diagnostics, antimicrobial resistance and the gut microbiome, infection prevention and control interventions, and the clinical development of new antimicrobial agents,
(https://medicinehealth.leeds.ac.uk/medicine/staff/3541/professor-mark-wilcox), including providing the basis of clinical advice to the NHS. He has been the Principal/UK Investigator for 16 clinical trials of new anti-infective drugs, 1999-2021. He has authored >550 papers and published a number of books and chapters.

– Ends –

For further information, please contact:

Destiny Pharma plc
Neil Clark, CEO
Shaun Claydon, CFO
pressoffice@destinypharma.com
+44 (0)1273 704 440

Optimum Strategic Communications
Mary Clark, Shabnam Bashir, Manel Mateus
DestinyPharma@optimumcomms.com
+44 (0) 203 174 1789

finnCap Ltd (Nominated Advisor Joint Broker)
Geoff Nash / Kate Bannatyne, Corporate Finance
Alice Lane, Corporate Broking
+44 (0) 207 220 0500

WG Partners (Joint Broker)
Nigel Barnes / Claes Spång / Nigel Birks
+44 (0) 203 705 9330

About Destiny Pharma
Destiny Pharma is a clinical stage, innovative biotechnology company focused on the development of novel medicines that can prevent life-threatening infections. Its pipeline has novel microbiome-based biotherapeutics and XF drug clinical assets including NTCD-M3, a Phase 3 ready treatment for the prevention of C. difficile infection (CDI) recurrence which is the leading cause of hospital acquired infection in the US and also XF-73 nasal gel, which is in a Phase 2b clinical trial targeting the prevention of post-surgical Staphylococcal hospital infections including MRSA. It is also co-developing SPOR-COV, a novel, biotherapeutic product for the prevention of COVID-19 and other viral respiratory infections and has earlier grant funded XF research projects.

For further information, please visit https://www.destinypharma.com